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SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Excellent
Based on 32 Reviews
9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Ubiquinol
100 mg
†
Top Medical Research Studies
9
Mitochondrial cocktail enhances heart protection
Melatonin/nicotinamide mononucleotide/ubiquinol: a cocktail providing superior cardioprotection against ischemia/reperfusion injury in a common co-morbidities modelled rat.
Ubiquinol's mixed impact noted
We designed a study with male Wistar rats, aged 22-24 months and induced with type-2 diabetes, to investigate how a combination of three mitochondrial agents—melatonin, nicotinamide mononucleotide (NMN), and ubiquinol—could provide protection against myocardial ischemia/reperfusion (I/R) injury, especially in the context of aging and diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
Read More
9
Combination therapy improves heart health
Superior Anti-arrhythmogenic Effect of Combined Conditioning with Nicotinamide Mononucleotide and Ubiquinol in Myocardial Ischemia/Reperfusion Injury in Aged Rats.
Combination limits individual assessment
We examined the combined effects of nicotinamide mononucleotide (NMN) and ubiquinol on heart health, particularly focusing on how they impact lethal heart rhythms following a heart attack in aged rats. The study involved 30 male Wistar rats, including groups with and without myocardial ischemia/reperfusion injury, as well as those receiving either NMN, ubiquinol, or both.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
Read More
Most Useful Reviews
9.5
Heart and brain health
I’ve been taking Co-Enzyme Q10 for over 25 years. This supplement is effective, though it won't cure all heart issues, especially with age. After experiencing chest pain that was ultimately diagnosed as not a heart attack, my cardiologist confirmed my arteries were clear. I credit my continued vitamin regimen with supporting my heart and brain health.
Read More
9
Vital energy boost
I first discovered coenzyme Q-10 after a heart attack. I've since moved to ubiquinol, which I felt working almost immediately. It gives me a sensation of vitality, improving ease of movement and cheerfulness. I find that taking it with Omega-3 and vitamin C enhances its effectiveness. The capsules are small and easy to swallow. I am thoroughly pleased with Jarrow Ubiquinol; it is clearly effective and worth the investment.
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9.5
Memory benefits noted
We started giving Ubiquinol to our mother for her congestive heart failure, but we were surprised to notice an improvement in her memory, which had been affected by dementia. After being on Aricept for two years, her condition stabilised. However, after a year of Co-Q 10, we’ve witnessed significant memory enhancement, which was an unexpected benefit.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
9
Combination therapy improves heart health
Superior Anti-arrhythmogenic Effect of Combined Conditioning with Nicotinamide Mononucleotide and Ubiquinol in Myocardial Ischemia/Reperfusion Injury in Aged Rats.
Combination limits individual assessment
We examined the combined effects of nicotinamide mononucleotide (NMN) and ubiquinol on heart health, particularly focusing on how they impact lethal heart rhythms following a heart attack in aged rats. The study involved 30 male Wistar rats, including groups with and without myocardial ischemia/reperfusion injury, as well as those receiving either NMN, ubiquinol, or both.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
Read More
9
Mitochondrial cocktail enhances heart protection
Melatonin/nicotinamide mononucleotide/ubiquinol: a cocktail providing superior cardioprotection against ischemia/reperfusion injury in a common co-morbidities modelled rat.
Ubiquinol's mixed impact noted
We designed a study with male Wistar rats, aged 22-24 months and induced with type-2 diabetes, to investigate how a combination of three mitochondrial agents—melatonin, nicotinamide mononucleotide (NMN), and ubiquinol—could provide protection against myocardial ischemia/reperfusion (I/R) injury, especially in the context of aging and diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
Read More
User Reviews
USERS' SCORE
Excellent
Based on 32 Reviews
9
9.5
Memory benefits noted
We started giving Ubiquinol to our mother for her congestive heart failure, but we were surprised to notice an improvement in her memory, which had been affected by dementia. After being on Aricept for two years, her condition stabilised. However, after a year of Co-Q 10, we’ve witnessed significant memory enhancement, which was an unexpected benefit.
Read More
9.5
Enhanced vitality experienced
After taking 200 mg of ubiquinol, I felt an immediate surge of strength and vitality. It also seemed to calm my nerves and alleviate heart attack symptoms. After a month, I noticed my stomach slimmed down, and it helped significantly during stressful moments. I truly believe ubiquinol is essential for daily health.
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9.5
Pregnancy health benefit
Ubiquinol is an excellent supplement, particularly beneficial for women preparing for a healthy pregnancy. I’ve found it increases energy levels significantly and improves health indicators. I would recommend it for anyone considering pregnancy or managing heart health, especially those on statins, as it can prevent heart attack risks.
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9.5
Essential statin support
Life Extension is truly excellent, and Jarrow offers a comparable product at a better price. This supplement is vital for anyone on statins or dealing with heart issues, as it significantly aids in preventing the risk of heart attack.
9.5
Prevents Heart Attack
I cannot be without this; it significantly reduces my heart palpitations. I feel much better since taking it—just one a day.
